Water in Organic Synthesis |
More and more chemists today are becoming curious about the use of water in organic synthesis, because there are many advantages linked with using such a safe and inexpensive solvent. Although the organic chemist has tended to shy away from using water in the past, it is now imperative that one understands how it might be used in organic synthesis.
Shū Kobayashi: “While most organic reactions have been carried out in organic solvents for a long time, negative aspects of organic solvents have come to the fore recently; many organic solvents are volatile, flammable, sometimes explosive, and have a damaging effect on human health or on the environment. Water is obviously the first choice of alternative solvent; water is clean, non-toxic, inexpensive, and the most environmentally benign. Water is really beautiful in nature, reactions are carried out in water in our bodies, mainly catalyzed by enzymes. Why should mankind not choose to use water in synthesis?”
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Water in Organic Synthesis
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